Relationship between Chemical Structure and Biological Activity Evaluated In Vitro for Six Anthocyanidins Most Commonly Occurring in Edible Plants

Numerous studies have provided evidence that diets rich in anthocyanins show a broad spectrum of health benefits. Anthocyanins nature are usually found the form glycosides. Their aglycone forms called anthocyanidins. The chemical structure is based on flavylium cation, but they differ position and number substituents. However, bioactives foods contain them frequently treated as uniform group compounds exhibiting same biological activity, without paying attention to structural differences between individual aim this study was find out how impact activity six most common dietary anthocyanidins, i.e., delphinidin (Dp), petunidin (Pt), cyanidin (Cd), malvidin (Mv), pelargonidin (Pg) peonidin (Po). concentrated redox-related phenomena compared following parameters: antioxidant (measured using various methods: spectrophotometric tests (ABTS, DPPH), ORAC assay CAA test (cellular activity)), ability inhibit growth human colon cancer cells (HT29; determined MTT assay), studied protect DNA from oxidative damage (comet assay). Based obtained results, relationship anthocyanidins their assessed. results revealed hydroxyl methoxy groups anthocyanidin strongly influenced not only color all activities.